Место работы автора, адрес/электронная почта: Республиканская больница N 1 Национальный центр медицины, Пульмонологическое отделение ; 677010, г. Якутск, ул. Сергеляхское шоссе, 4 ; e-mail: rb1ncm@mail.ru ; https://rb1ncm.ru/
ID Автора: РИНЦ AuthorID: 565716
Деятельность: Ведущий пульмонолог РБ N1-НМЦ.
Количество страниц: 4 с.
The article presents the results of studying the clinical course of cyctic fibrosis (CF) in children in the Sakha Republic (Yakutia). In our analysis of the genetic examination, the leading genetic mutations were a del F 508 mutation in the homozygous and heterozygous state. All the observed patients had a mixed form of CF. There were 5 patients with a severe course, and 4 with a moderate course. The severity of clinical manifestations largely depends on the severity of the course of the disease. The most pronounced changes were observed from the respiratory and pancreatic systems. Pancreatic insufficiency, bronchitis and respiratory insufficiency come to the fore. During the sweat test, all children with CF had an increase in its parameters by one and a half or more times. According to the results of CPG, there was a violation of the digestive function and pancreatic system. When analyzing the instrumental data, the majority of children experienced changes in the radiograph in the form of bronchitis, diffuse changes from the liver and pancreas to ultrasound examination of the abdominal cavity organs, cardiac dysfunction on the electrocardiogram. A number of patients showed such changes as compaction of renal sinuses, bilateral purulent bronchitis, and pancreatic atrophy. All the observed patients received constant complex basic medical therapy: minimicrospheric pancreatic enzymes (at an individual calculated dosage), mucolytic drugs (according to the individual scheme), bronchospasmolytics (according to indications), antibacterial therapy (according to an individual plan, depending on the period of the disease and the data of the microbiological result in sputum cultures), vitamin therapy (including fat-soluble vitamins in elevated dosages), choleretic therapy and hepatoprotectors, and performedobligatory individual program of kinesitherapy (special breathing exercises and chest compressions)
Клиническое течение муковисцидоза у детей в условиях Республики Саха (Якутия)/Т. И. Никифорова, М. В. Ханды, А. И. Черноградский [и другие]//Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2017. — N 4 (09). — С. 65-68.
Количество страниц: 4 с.
Ханды, М. В. Дефицит Альфа-1 антитрипсина у ребенка в Республике Саха Якутия / М. В. Ханды, Т. И. Никифорова, Л. Е. Николаева // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки.— 2019. — N 1 (14). — С. 47-50. — DOI: 10.25587/SVFU.2019.1(14).27476
DOI: 10.25587/SVFU.2019.1(14).27476
Количество страниц: 2 с.
The article is devoted to the observation over a period of 3 years (2014-2017) of a clinical case of bronchiectatic disease in a 16-year-old teenager. The child was disturbed by complaints of shortness of breath during physical exertion, a wet cough with purulent sputum. From an early age, often, up to about 5 times a year, he suffered from bronchitis with obstructive syndrome. In 2014, he was hospitalized in the pulmonology department with a diagnosis of Community-acquired pneumonia, moderate lobe, moderate. According to the results of computed tomography of the chest organs, the conclusion is made: bronchiectasis of the middle lobe of the right lung.
Клинический случай бронхоэктатической болезни у подростка 16 лет / Л. Е. Николаева, О. Н. Иванова, Е. Ф. Аргунова // Якутский медицинский журнал. — 2018. — N 1 (63). — С. 90-91.
DOI: 10.25789/YMJ.2018.63.27
Количество страниц: 2 с.
Native and non-native adolescents of the Sakha (Yakutia) Republic and Khabarovsk were surveyed. The features of the phenotypic characteristics of peripheral blood lymphocytes in the young indigenous of Yakutia were revealed. The revealed regional features of the immune status of Sakha (Yakutia) Republic adolescents are considered as adaptive, aimed at compensation of the effects of climatic, technological and emotional environmental factors
Особенности показателей клеточного звена иммунитета у подростков Дальневосточного региона / М. И. Самсонова, М. В. Ефименко, А. С. Соловьева, Т. Е. Бурцева, Л. Е. Николаева // Якутский медицинский журнал. – 2013. – N 1 (41). – С. 15-16.