Молекулярная эпидемиология вируса гепатита В в Якутии
Статья в журнале
Русский
Библиогр.: с. 57 (11 назв.)
616.36-002(571.56)
гепатит В; генотипы; вирусная нагрузка; мутации; лекарственная устойчивость; hepatitis B; genotypes; viral load; mutations; drug resistance
Гастроэнтерология и гепатология
Якутский медицинский журнал. – 2014. – N 3 (47) (С. 54-57)
Heterogeneity of hepatitis B virus and its link with clinical course of infection and its outcomes remains one of priority directions of researches in Republic Sakha (Yakutia), as the region with high incidence of this disease. Blood serum samples with chronic hepatitis, registered in dispensary of various regions of the Republic Sakha (Yakutia), have been investigated. On the basis of results of the research by means of molecular – biological methods in the republic a genotype D was considered as the dominating genotype at patients with CHB, and sufficiently a large number of patients are infected simultaneously by two genotypes, most intensively circulating in the territory of Republic (A, D, C). For adequate therapy of such diseases it is necessary to consider characteristics of excreted isolates.
Молекулярная эпидемиология вируса гепатита В в Якутии / В. В. Герасимова, Н. Р. Максимова, И. А. Левакова, С. Л. Мукомолов // Якутский медицинский журнал. – 2014. – N 3 (47). – C. 54-57.
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