Количество страниц: 8 с.
- Общественные науки. Образование > Народное образование. Воспитание. Обучение. Организация досуга > Высшее образование. Высшая школа. Подготовка научных кадров,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Гигиена. Санитария,
- НАУКА ЯКУТИИ > ОБЩЕСТВЕННЫЕ НАУКИ > Народное образование. Воспитание. Обучение. Организация досуга > Высшее образование. Высшая школа. Подготовка научных кадров,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Гигиена. Санитария.
- 1. Матаннанова Анна Николаевна, Трифонов Евгений Павлович. Дистанционное обучение в информационно-образовательной среде: планирование системы уроков химии = Оnline learning in the information and educational environment: planning chemistry lessons system
- 2. Жондорова Галина Егоровна. Становление университетского филологического образования в Якутии = Formation of university philological education in Yakutia
- 3. Панина Светлана Викторовна, Донская Ариадна Андреевна, Петрова Милана Николаевна, Борисова Екатерина Петровна. Содействие профессиональной медицинской ориентации школьников = Promoting professional mediсal career in schoolchildren
- 4. Вестник Северо-Восточного федерального университета им. М. К. Аммосова, 2024, №1 (95)
- 5. Вестник Северо-Восточного федерального университета им. М. К. Аммосова, 2024, №4 (98)
The article discusses the issue of developing the skills and actions of students in emergency situations in educational organizations. One of the modern, technological and effective solutions for developing the skills of action in such situations are immersive simulators. Immersive simulators are implemented both on stationary PCs and in VR systems. With the advent of new and more accessible virtual reality systems, immersive simulators are gaining popularity in education. Versions of immersive simulators for personal computers are gaining popularity. Practicing the necessary skills in immersive simulators allows you to create an absolutely safe learning environment. Students can practice the necessary skills without risk to their lives and make decisions in various emergency situations. This type of training allows consistent and algorithmically thoughtful performance of the necessary actions, increases the level of a person’s training in critical situations, improves reaction and helps to preserve life. Based on the list of emergency situations, an immersive simulator was developed to teach students how to respond to emergency situations in educational institutions. The process of developing an immersive simulator in the Unity environment using the ProBuilder tool is disclosed. A system of criteria for recording the results of training on an immersive simulator were developed. An experiment on the use of the developed immersive simulator as a means of practicing skills and actions in emergency situations is described. The results confirming its effectiveness are presented. Ways for its further improvement and expansion of functional capabilities are proposed.
Корнилов, Ю. В. Применение иммерсивных технологий для обучения студентов действиям в чрезвычайных ситуациях в образовательных учреждениях / Ю. В. Корнилов, Л. О. Угаров ; Северо-Восточный федеральный университет им. М. К. Аммосова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия "Педагогика. Психология. Философия" - 2024. - N 4 (36). - С. 74-81. - DOI: 10.25587/2587-5604-2024-4-74-81
DOI: 10.25587/2587-5604-2024-4-74-81
Количество страниц: 6 с.
Ап algorithm for assessing the professional potential of an otorhinolaryngologist based on the identification of medical risk factors in the provision of medical care to patients with rhinosinusitis has been developed, otorhinolaryngologists from 32 subjects of the Russian Federation were screened and the treatment of patients with polyposis rhinosinusitis was analyzed. The proposed methodological approach was successfully used to assess the knowledge and skills of physicians of other specialties and formed the basis for the methodology of studying the professional potential of physicians, for which the author's invention certificates were also obtained
Методология определения медицинской детерминанты общественного здоровья с выявлением медицинских факторов риска нарушения здоровья в оториноларингологии (на примере анализа лечения полипозного риносинусита) = Methodology for determining the medical determinant of public health with the identification of medical risk factors for health disorders in otorhinolaryngology (on the example of analyzing the treatment of polyposis rhinosinusitis) / С. В. Русских, Е. Л. Савлевич, Т. П. Васильева, Е. А. Тарасенко, Л. Н. Афанасьева, А. В. Шурупина, Ю. В. Арсенина ; НИИ общественного здоровья им. Н. А. Семашко, МОНИКИ им. М. Ф. Владимирского, Северо-Восточный федеральный университет им. М. К. Аммосова // Якутский медицинский журнал. - 2024. - N 3, (87). - С. 57-62. Рез. также англ. - Библиогр.: с. 61-62 (14 назв.). - Разработан алгоритм оценки профессионального потенциала врача-оториноларинголога на основе выявления медицинских факторов риска при оказании медицинской помощи пациентам с риносинуситом. Проанкетированы врачи-оториноларингологи из 32субъектов РФ и проведен анализ лечения пациентов с полипозным риносинуситом. Методический подход был успешно апробирован для оценки знаний и умений врачей других специальностей и положен в основу методологии изучения их уровня профессионального потенциала. - Ап algorithm for assessing the professional potential of an otorhinolaryngologist based on the identification of medical risk factors in the provision of medical care to patients with rhinosinusitis has been developed, otorhinolaryngologists from 32 subjects of the Russian Federation were screened and the treatment of patients with polyposis rhinosinusitis was analyzed. The proposed methodological approach was successfully used to assess the knowledge and skills of physicians of other specialties and formed the basis for the methodology of studying the professional potential of physicians, for which the author's invention certificates were also obtained.
DOI: 10.25789/YMJ.2024.87.11
Количество страниц: 8 с.
Diamond-Blackfan anemia (DBA) is a rare form of congenital red cell aplasia of hematopoiesis in infants and children, characterized by suppression of erythropoiesis and congenital malformations. The article presents an observation of a child with DBA. The girl was born with severe anemia. The diagnosis was established at the age of 3 months, genetically confirmed at 2 years. Since her birth, she had been receiving monthly transfusion therapy with red blood cells. Treatment with prednisolone, L-leucine was carried out without effect, the child remained transfusion-dependent. The only curative method for this disease is hematopoietic stem cell transplantation (HSCT). With a 14-year-old sibling not suitable, there was no other suitable related donor. By the age of 15, the child had developed serious complications caused by post-transfusion iron overload of the liver (grade 4), myocardium, pituitary gland with the development of liver and heart failure; endocrine disorders in the form of hypopituitarism, primary and secondary hypothyroidism, increased fasting glycemia. In addition, the girl has chronic viral hepatitis C. In order to remove excess iron from the body, the patient has been receiving chelation therapy since the age of 8. The accumulation of iron in organs leads to irreversible dysfunction, reducing the life expectancy of patients with DBA, so early initiation of chelation therapy is necessary.
Анемия Даймонда-Блекфена с тяжелой пострансфузионной перегрузкой железом / Аргунова Е. Ф., Харабаева Е. М., Протопопова Н. Н., Кондратьева С. А. [и др.] ; Северо-Восточный федеральный университет им. М.К. Аммосова, Медицинский институт, ГАУ РС (Я) "Республиканская больница N 1 - Национальныйцентр медицины имени М. Е. Николаева" // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки. - 2024. - N 4 (37). - C. 10-17. - DOI: 10.25587/2587-5590-2024-4-10-17
DOI: 10.25587/2587-5590-2024-4-10-17
Количество страниц: 11 с.
The article presents the results of the amino acid composition of urine in children with connective tissue disorders (undifferentiated connective tissue dysplasia syndrome - uCTD) living in the Republic of Sakha (Yakutia). Connective tissue disorders are associated with complex metabolic changes, including amino acid metabolism in children. However, currently available data are contradictory. The aim of this study was a comprehensive assessment of connective tissue disorders, as well as a comparative analysis of the amino acid levels in the urine of healthy children and children with uCTD. Materials and methods. The present study included 524 children who were part of the control group and 1266 children with undifferentiated connective tissue dysplasia syndrome included in the experimental group. The level of amino acids in the urine of 105 children was assessed using gas chromatography. Statistical analysis was performed using the SPSS program, version 22. Results and discussion. It has been established that the levels of amino acids in the urine of children provide information on the existing imbalance, which indicates, among other things, nutritional and metabolic disorders underlying a large number of diseases, including disorders associated with connective tissue. It is concluded that increased excretion of various amino acids in the urine of children with undifferentiated CTD syndrome may be a consequence of impaired protein synthesis due to the absence (or deficiency) of any amino acids in the diet.
Нохсорова, М. А. Нарушение соединительной ткани и метаболические изменения у детей, проживающих в Республике Саха (Якутия) / Нохсорова М. А., Борисова Н. В., Аммосова А. М. ; Медицинский институт Северо-Восточный федеральный университет им. М. К. Аммосова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки. - 2024. - N 4 (37). - C. 88-98. - DOI: 10.25587/2587-5590-2024-4-88-98
DOI: 10.25587/2587-5590-2024-4-88-98
Количество страниц: 10 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Гигиена. Санитария,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Стоматология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Стоматология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Гигиена. Санитария.
An analysis of literary sources characterizes the presence of numerous harmful factors, accompanying professional activities of dentists. The article considers the influence of harmful factors on the health of dentists, which cause the emergence and development of occupational pathological conditions. The main risk factors are psychoemotional professional burnout; stressful situations; constant noise from devices and equipment; prolonged uncomfortable positions of the doctor’s body when providing dental care; frequent contact with harmful substances, affecting the respiratory system and skin; proximity of the “operative field” when working with infected patients. Harmful occupational factors contribute to the development of hearing impairment, neurological and skin diseases, respiratory and musculoskeletal diseases, as well as infectious diseases. The relevance of an integrated approach to reduce the risk of developing occupational somatic pathology is substantiated. The main goal of work in medical and preventive institutions of the dental profile is to create optimal conditions for the work of medical personnel in accordance with the requirements of modern science and occupational health, to increase productivity and maintain strength and health. To date, the prevention of harmful factors in the profession of a dentist is an important aspect of ensuring his health and safety. At the same time, in order to reduce the harmful effect of various working factors in the work of a dentist, it is necessary to observe ergonomic principles of labor organization. In addition, compliance with sanitary and anti-epidemiological rules in the workplace should be combined with the allocation of time for rest and the restoration of the compensatory and adaptive potential of the body. One of the important factors in maintaining the psychological well-being of medical workers and their stress resistance is the prevention of professional emotional burnout of specialists. In this regard, timely training in stress management and psychological support in the team is an extremely important factor. At the same time, it is important to constantly comply with the rules of balanced nutrition. Paying attention to daily exercise and outdoor activities, it is also necessary to undergo timely examination and compliance with sanitary and hygienic rules contribute to the prevention of possible problems.
Клиническая характеристика вредныхпрофессиональных факторов, влияющих на здоровье врача-стоматолога (системный обзор) / Чижов Ю. В., Ушницкий И. Д., Казанцева Т. В., Михасько В. М., Непомнящий А. В. [и др.] ; Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого, Медицинский институт Северо-Восточный федеральный университет им. М. К. Аммосова, Красноярская городская стоматологическая поликлиника N 8, Клиника "Алексия", Клиника "Алдент", Дальневосточный государственный медицинский университет // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки. - 2024. - N 4 (37). - C. 69-78. - DOI: 10.25587/2587-5590-2024-4-69-78
DOI: 10.25587/2587-5590-2024-4-69-78
Количество страниц: 9 с.
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease within the spectrum of motor neuron disorders, selectively targeting central and peripheral motor neurons in the brain and spinal cord, with highly variable clinical manifestations. One rare form of ALS is progressive muscular atrophy (PMA), primarily characterized by the selective involvement of peripheral motor neurons and a slower, less aggressive progression compared to classical ALS. Currently, the scientific community lacks consensus on whether PMA should be classified as a distinct nosological entity or as a subtype of ALS. Recent advancements in genetic research have identified that familial and hereditary forms of ALS are most frequently linked to mutations in the SOD1, TARDBP, C9orf72, and FUS genes, among others. Moreover, increasing progress in genetic testing now enables the identification of mutant genes responsible for various phenotypes. Understanding the genetic underpinnings of motor neuron diseases is crucial for elucidating their pathogenesis, which may pave the way for the development of novel diagnostic and therapeutic strategies. This article presents a clinical case involving a patient with a PMA phenotype associated with the H49R mutation in the SOD1 gene. A comprehensive account of the patient’s anamnesis, clinical presentation, molecular-genetic findings, as well as results from instrumental investigations, including electromyography and magnetic resonance imaging, is provided. The article discusses the potential nosological autonomy of PMA and its association with the H49R mutation, referencing current data from both Russian and international studies. Additionally, the article highlights the challenges of differential diagnosis, particularly in distinguishing PMA from other neurodegenerative diseases with similar clinical profiles. This case contributes to the expanding knowledge of the heterogeneity of motor neuron diseases and underscores the importance of molecular-genetic testing in predicting disease prognosis and guiding patient management.
Мутация H49R гена SOD1 как причина развития прогрессирующей мышечной атрофии: клинический случай / Сыромятников Н. Н., Таппахов А. А., Давыдова Т. К., Конникова Э. Э., Хабарова Ю. И. ; Медицинский институт Северо-Восточный федеральный университет им. М. К. Аммосова, Якутский научный центр комплексных медицинских проблем // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки. - 2024. - N 4 (37) - C. 60-68 - DOI: 10.25587/2587-5590-2024-4-60-68
DOI: 10.25587/2587-5590-2024-4-60-68
Источник: Вестник Северо-Восточного федерального университета им. М. К. Аммосова. - 2024. - N 4 (37).
Количество страниц: 10 с.
Течение хронического гепатита D у коренного населения Республики Саха (Якутия) / Заморщикова О. М., Слепцова С. С., Слепцов С. С. ; Медицинский институт Северо-Восточный федеральный университет им. М. К. Аммосова, Якутский научный центр комплексных медицинских проблем // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. - 2024. - N 4 (37). - C. 42-51. - DOI: 10.25587/2587-5590-2024-4-42-51
DOI: 10.25587/2587-5590-2024-4-42-51
Количество страниц: 7 с.
This research says that lichen ruber planus (LRP) has a wide range of clinical manifestations in the oral cavity, where the main morphological element of the lesion is papular rashes accompanied by inflammatory and proliferative processes. At the same time, the etiological factors and pathogenetic mechanisms of development are currently not fully understood. In many pathological conditions of the body, oxidative stress plays a leading role in the mechanism of damage to the structure of cell membranes, violation of their permeability, which is associated with increased production of reactive oxygen species, which have a pronounced reactive effect. For the state of oxidative stress (OS), first of all, it is typical to have an imbalance in the ratio of the pro- and antioxidant systems in the direction of strengthening the former, which possibly contributes to the development of inflammatory and destructive lesions in the COPR with CPL. The aim of the study was to study the activity of free radical processes in the blood serum of patients with CPL COPR for a selective approach to the appointment of corrective therapy. Materials and methods of research. The study of biochemiluminescence parameters was carried out in 66 recipients with CPL SOPR, age group from 35 to 65 years and a control group that included 33 people of similar age, without clinical manifestations of diseases of SOPR. The intensity of free radical processes in blood serum was assessed by chemiluminescence (CML) using the LS 50B “PERKIN ELMER” spectrometer. Spontaneous, Fe2+-induced and H2O2-initiated chemiluminescence in the presence of luminol was recorded. The obtained data were displayed in relative units. Results. The obtained results by the method of chemiluminescence (CML) in serum in recipients with clinical LRP manifestations in the oral cavity determine the dynamic characteristic of intensification of free-radical processes. At the same time, actual data on the weakening of the antioxidant protection systems barrier (Ssp, h, Sind-1, Slum, H and Sind-2) were revealed compared to similar data of the control group. Discussion. CML indicators reflect an increase in the production of free radicals of a lipid nature and a weakening of the antioxidant barrier in individuals with CPL COPR, which indicates the development of OS in the body as a whole. Conclusion. Taking into account the development of the state of systemic OS in CPL COPR, it is justified to correct it in a timely manner by including antioxidants in the general treatment complex to reduce the duration of manifestations of lesions and to provide a positive effect of the therapy.
Активность свободно-радикальных процессов в сыворотке крови у больных красным плоским лишаём слизистой оболочки полости рта/ Загородняя Е. Б., Ушницкий И. Д., Юркевич А. В., Сувырина М. Б. [и др.] ; Дальневосточный государственный медицинский университет, Медицинский институт Северо-Восточный федеральный университет им. М. К. Аммосова, Хабаровский военный госпиталь, Кемеровский государственный университет // Вестник Северо-Восточногофедерального университета им. М. К. Аммосова. - 2024, N 4 (37). - C. 35-41. - DOI: 10.25587/2587-5590-2024-4-35-41
DOI: 10.25587/2587-5590-2024-4-35-41
Количество страниц: 9 с.
Meningococcal infection (MI) is a current disease with a wide range of clinical manifestations and an aggressive course. The clinical picture of meningococcal infection is characterized by polymorphism of manifestations from asymptomatic to extremely severe forms, leading to death within a few hours. The risk group for MI are children under 5 years of age. The GFMI can be caused by 6 serogroups: A, B, C, W, X and Y. Serotype W had not been registered in the Sakha Republic (Yakutia) until recently. With the MI caused by Neisseria meningitidis W, a number of authors note the polymorphism of the clinical picture of the generalized form of meningococcal infection. The presence of various atypical manifestations is characteristic. The article presents three clinical cases of patients with generalized meningococcal infection caused by Neisseria meningitidis, two of whom had the disease caused by serogroup W. Three young patients with similar clinical picture had no contacts confirmed by epidemiological investigation. All three had an atypical onset of the disease, with gastrointestinal syndrome. Eventually, all developed the clinical picture of severe meningoencephalitis. The peculiarity of these cases is isolated meningoencephalitis, without meningococcemia, which is the least common among generalized forms of meningococcal infection. Two patients were diagnosed with mixed infection with Epstein-Barr virus. One patient developed arthritis, according to the classification, related to rare forms of MI. In all patients, the outcome of the disease was sensorineural hearing loss.
Атипичное течение генерализованной формы менингококковой инфекции серотипа W у детей раннего возраста / Дмитриева Т. Г., Кожухова Ж. В., Суздалова В. П., Мамонтова С. М., Агаева Л. З. К. ; Северо-Восточный федеральный университет им. М. К. Аммосова, Медицинский институт, ГБУ "Детская клиническая инфекционная больница" // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Медицинские науки. - 2024. - N 4 (37). - C. 26-34. - DOI: 10.25587/2587-5590-2024-4-26-34
DOI: 10.25587/2587-5590-2024-4-26-34
Ответственность: Слепцова Снежана Спиридоновна (Составитель), Кершенгольц Борис Моисеевич (Составитель), Колосова Ольга Николаевна (Составитель), Шашурин Михаил Михайлович (Составитель), Николаева Евгения Николаевна (Составитель), Петрова Пальмира Георгиевна (Автор обозрения, рецензии), Татаринова Ольга Викторовна (Автор обозрения, рецензии)
Издательство: Издательство ФГБУН Институт мерзлотоведения им. П. И. Мельникова СО РАН
Год выпуска: 2024
Количество страниц: 28 с.
Биологически активная добавка "Бетукладин" в профилактике дезадаптационных состояний организма человека и реабилитации при новой коронавирусной инфекции Covid-19 :информационно-методическое письмо / Министерство здравоохранения Республики Саха (Якутия), Северо-Восточный федеральный университет имени М. К. Аммосова, Институт биологических проблем криолитозоны Федерального исследовательского центра "Якутский научный центр Сибирского отделения Российской академии наук" ; составители: С. С. Слепцова, Б. М. Кершенгольц, О. Н. Колосова [и др.] ; рецензенты: П. Г. Петрова, О. В. Татаринова. - Якутск : Издательство ФГБУН Институт мерзлотоведения им. П. И. Мельникова СО РАН, 2024. - 21 с. : ил., табл., диагр. - 200 экз.